Elizabeth Renfro

Elizabeth Renfro (a.k.a. Madame X) was a former director of Manticore.

Biography
An attractive but extremely dangerous and sadistic woman who seemed to relish being cruel, Renfro was Lydecker's superior. Unlike "Deck", who feels a twisted-yet-genuine attachment to his fugitive kids, Renfro wanted the renegade X5s recaptured or neutralized by whatever means necessary. Amazingly, however, Renfro sacrificed her life in order to save Max Guevara, mysteriously revealing with her dying breath that Max possesses unique and valuable genetic characteristics and that she must find Sandeman. While never stated outright in the series, it is intimated that she may have connections to the Breeding Cult, as both Renfro and the men White hired to kidnap his son have RCF identity cards that access the Coloma burial site. Presumably, despite her obvious evil, she was an enemy of the cult and was trying to carry out Sandeman's plan to immunize the human race from their virus using Max.

Behind the Scenes

 * Episode writer commentary on the DVDs and interviews with Nana Visitor indicated that Renfro was using transgenic DNA to extend her lifespan and could have been much older than she appeared.